3-O-Benzhydryl-2,5-dideoxy-2,5-imino-2-C-methyl-l-lyxono-1,4-lactone
نویسندگان
چکیده
The title bicyclic lactone, C(19)H(19)NO(3), is an inter-mediate in the synthesis of chiral α-methyl-prolines and branched C-methyl pyrrolidines; the absolute configuration was determined by the use of d-erythronolactone as the starting material. It exhibits no unusual crystal packing features, and each mol-ecule acts as a donor and acceptor for one C-H⋯O hydrogen bond.
منابع مشابه
2-O-Benzhydryl-3,4-(S)-O-benzylidene-d-lyxono-1,4-lactone
X-ray crystallography unequivocally showed that protection of the free hydroxyl group of 3,5-O-benzyl-idene-d-lyxono-1,4-lactone with diphenyl-diazo-methane proceeded with retention of configuration to give the title compound, C(25)H(22)O(5). The crystal structure consists of layers of inter-locked mol-ecules lying parallel to the a axis.
متن کامل2-O-Benzhydryl-3,4-(S)-O-benzylidene-d-xylono-1,4-lactone
X-ray crystallography unequivocally shows that protection of the free hydroxyl group of 3,5-O-benzyl-idene-d-xylono-1,4-lactone with diphenyl-diazo-methane proceeded smoothly to give the title compound, C(25)H(22)O(5), with no accompanying epimerization. Unlike the analogously protected lyxono lactone, the isomeric xylono lactone has two mol-ecules present in the asymmetric unit (Z' = 2). The 5...
متن کاملN-(2-Carboxyethyl)-2,5-dideoxy-2,5-imino-d-mannonic acid [(3R,4R,5R)-1-(2-carboxyethyl)-3,4-dihydroxy-5-hydroxymethyl-l-proline]
The absolute stereochemistry of the title compound, C(9)H(15)NO(7), was determined from the use of d-glucuronolactone as the starting material. The compound crystallizes as the zwitterion. The five-membered ring adopts an envelope conformation with the -CH(2)OH-substituted C atom forming the flap. An intramolecular N-H⋯O hydrogen-bond occurs. In the crystal, the compound exists as a three-dimen...
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متن کامل2-N-Benzyl-2,6-dideoxy-2,6-imino-3,4-O-isopropylidene-3-C-methyl-d-allononitrile
X-ray crystallography firmly established the relative stereochemistry of the title compound, C(17)H(22)N(2)O(3). The absolute configuration was determined by use of 2-C-methyl-d-ribonolactone as the starting material. The compound exists as O-H⋯N hydrogen-bonded chains of mol-ecules running parallel to the a-axis.
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